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ADAMTS4 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
ADAMTS4 Protein
Descriptor
Spanish
:
Proteína ADAMTS4
Descriptor
Portuguese
:
Proteína ADAMTS4
Synonyms
English
:
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein
ADAMTS-4 Protein
Aggrecanase-1
ADAMTS 4 Protein
Aggrecanase 1
Tree Number:
D08.811.277.656.675.374.102.500.844
D09.400.430.500.500.844
D12.776.395.033.500.844
D12.776.860.300.085.844
Definition
English
:
An ADAMTS protease
similar
to
ADAMTS5 PROTEIN
. It contains a single C-terminal
thrombospondin
(TS) motif and cleaves AGGRECAN in
CARTILAGE
. It may also be involved in the destruction of aggrecan in
ARTHRITIS.
History Note
English
:
2017 (1999)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56488
Unique Identifier:
D000071121
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS